Each lozenge contains 3mg of plant-derived melatonin from Griffonia and 500mg of vitamin B6.

Usual use: One sublingual lozenge at bedtime or as directed by your doctor. Let the lozenge dissolve slowly under the tongue.

With natural mint flavor.

Precautions: Not to be used by people under 25 or by pregnant and lactating women without medical advice.

~ Gluten free

~ For vegetarians

~ Natural product without dyes

Nature's Plus Co-Mel contains the exact levels of vitamin B6 and melatonin that are considered essential for the body and is therefore a useful aid in the treatment of insomnia and works against the disruption of the biological cycle that occurs when people travel across time zones (jet lag).

Vitamin B6 is a water-soluble vitamin found in 3 forms: pyridoxine, pyridoxamine and pyridoxal.

Melatonin is a hormone produced by the brain, specifically by the pineal gland, from the amino acid tryptophan. It helps the body know when it's time to go to sleep and when it's time to wake up. Melatonin synthesis and secretion in the brain is activated by darkness and inactivated by light.

The concentration of melatonin in the blood reaches its highest levels just before sleep. It has antioxidant properties and increases the production of T-type lymphocytes which are a key pillar of the immune system's defensive capacity.

Specifically, and based on EFSA's official claims, melatonin helps to reduce sleep onset time. It also helps relieve the symptoms of jet lag. Vitamin B6 contributes to the normal functioning of the nervous system. *

* The above information about vitamin B6, melatonin is an official health claim from the European Food Safety Authority (EFSA), EU Regulation no. 432/2012, No. · 8 (2): 1467 [Melatonin], 2011 · 9 (6): 2241 [Melatonin]